After trying to read everyone's posts, I realize that I care much more about questions involving roster construction than stats. Anyway, I do not like negative stats. But, if people really want to have them, we need a negative stat for both hitters and pitchers, to avoid completely unbalancing their respective values. I still like defense, but agree that the available stats are worthless.
Also, I like counting stats much more than %.
I have a weak preference for the following...
Hittings: TB, R, RBI, SB, BB
Pitching: W, SV, K, Outs Recorded, Pitching Appearances